We are growing and looking for a few great folks to join our team! We are expanding our research efforts and are looking for committed team players interested in making a difference in the lives of individuals living with neurodegenerative disorders including MS. Studies will span basic cell analyses through to more complex models and ultimately translation of these findings to human systems and disorders.
Focus project areas:
- Imaging and therapeutic strategies in preclinical models of neuroinflammatory disorders
- Limiting inflammation and activation of the blood-brain barrier
- Biomarker analyses in relevant clinical groups
- Environmental influence upon inflammatory and neuroprotective proteins and processes relevant to multiple sclerosis and other neurodegenerative disorders.
Research assistant: This is a terrific position for a person that wants to actively contribute to answering questions in research related to neuroinflammation and neurodegeneration. The position involves some administration but greater commitments to data generation and analyses to help us achieve our research aims.
The UBC posting will be up in the next few days as we look to consider a gradual return to research once research curtailments are lifted.
Post-doctoral fellow or Graduate student
Graduate Program in Pathology & Laboratory Medicine or Graduate Program in Neuroscience: Candidates for a graduate student position can expect to gain training and expertise in a number of the techniques below. Possible projects will focus on:
Post-doctoral fellowship in Pathology & Laboratory Medicine: Candidates with expertise in neuroscience/immunology related cell culture, molecular biology, murine preclinical and behavioural models are encouraged to apply for the Post-Doctoral position, where advanced training prior to joining the laboratory are requisite. The successful candidate will undertake a research project aimed to examine factors that regulate neuroprotective proteins in both neurons and glia both in the peripheral immune and within the central nervous system.
Training & expectations: Major areas of focus will include inflammatory mediators, oxidative stress, environmental stressors, immune populations, neurodegeneration and repair. While graduate students accepted for the position can expect to receive training and proficiency in a number of the following, the candidate for a PDF position should have a solid understanding and demonstrated proficiency in several of the following:
- Cell culture and aseptic technique, preferably involving both isolation and maintenance of rodent primary cultures as well as cell lines.
- Aseptic technique and experience with human blood handling for the isolation of PBMC and subsequent culture/assay
- Ability to perform and troubleshoot molecular and cellular biology techniques: RNA/DNA isolation, quantitative PCR, transfection, siRNA knockdown and cDNA construct knockin, flow cytometry, immunohisto- and cytochemistry on cells as well as tissues, fluorescence and light microscopy; conventional and/or confocal; ELISA, protein isolation and western blotting;
- Comprehensive understanding of experimental design and assay optimization is important along with ability to work well with others and to work independently.
- Willingness to work with small rodents. Applicants with experience in pre-clinical models of neurodegenerative diseases including MS are especially encouraged to apply.
- Maintenance/monitoring of colonies of transgenic animals, including breeding, screening and management.
- Excellent verbal and written communication skills including manuscript preparation, data presentation and discussion in group settings and at meetings and/or conferences
Interested candidates should send a statement of research interests and an updated CV to firstname.lastname@example.org. Inquiries will be reviewed on a rotating basic until positions have been filled.
Post Doctoral fellow start date: Spring/summer 2020 or position may be held for an outstanding candidate
Graduate student start date: Summer/fall 2020