We are growing and looking for a few great folks to join our team! We are expanding our research efforts and are looking for committed team players interested in making a difference in the lives of individuals living with neurodegenerative disorders including MS. Studies will span basic cell analyses through to more complex models and ultimately translation of these findings to human systems and disorders.
Focus project areas:
- Imaging and therapeutic strategies in preclinical models of neuroinflammatory disorders
- Limiting inflammation and activation of the blood-brain barrier
- Biomarker analyses in relevant clinical groups
- Environmental influence upon inflammatory and neuroprotective proteins and processes relevant to multiple sclerosis and other neurodegenerative disorders.
*TWO Research assistant positions: This is a terrific position for a person that wants to actively contribute to answering questions in research related to neuroinflammation and neurodegeneration. The position involves some administration but greater commitments to data generation and analyses to help us achieve our research aims.
Research assistant start date: January 2021
The UBC posting can be found here:
Post-doctoral fellowship in Pathology & Laboratory Medicine: Candidates with expertise in neuroscience as well as immunology related cell culture, molecular biology, murine preclinical and behavioural models are encouraged to apply. Relevant advanced training prior to joining the laboratory are requisite. The successful candidate will undertake a research project aimed to examine factors that regulate neuroprotective proteins in both neurons and glia both in the peripheral immune and within the central nervous system.
Post Doctoral fellow start date: Spring/Summer 2021 (position may be held for an outstanding candidate)
**Please note: UBC limits PDF appointments to those that are within 5 years of obtaining their PhD degree. Applicants more than five years from obtaining their PhD degree are not eligible.
Interested candidates for the PDF position will not apply through the UBC job site: instead please send a statement of research interests and CV with publication record along with THREE letters of reference to firstname.lastname@example.org. Inquiries will be reviewed on a rotating basic until positions have been filled.
Training & expectations: Major areas of focus will include inflammatory mediators, oxidative stress, environmental stressors, immune populations, neurodegeneration and repair. Candidates should have a solid understanding and demonstrated proficiency in a number of the following:
- Cell culture and aseptic technique, preferably involving both isolation and maintenance of rodent primary cultures as well as cell lines.
- Ability to perform and troubleshoot molecular and cellular biology techniques: RNA/DNA isolation, quantitative PCR, transfection, siRNA knockdown and cDNA construct knockin, flow cytometry and functional immune cell assays, immunohisto- and cytochemistry on cells as well as tissues, fluorescence and light microscopy; conventional and/or confocal; ELISA, protein isolation and western blotting;
- Comprehensive understanding of experimental design and assay optimization is important along with ability to work well with others and to work independently.
- Willingness to work with small rodents. Applicants with experience in pre-clinical models of neurodegenerative diseases including MS are especially encouraged to apply.
- Maintenance/monitoring of colonies of transgenic animals, including breeding, screening and management.
- Excellent verbal and written communication skills